Brian Michel

Assistant Professor

What I do

I teach and do research in the field of organic chemistry with special focus on design of small-molecule fluorescent probes and development of new methodologies utilizing transition metal catalysis.

Professional Biography

BS from Western Washington University in 2006
PhD from University of Utah in 2011
Postdoctoral Scholar University of California, Berkeley 2011-2014
American Heart Association Postdoctoral fellow 2013-2014
Assistant Professor, University of Denver 2014-present

Degree(s)

  • Ph.D., Organic Chemistry, University of Utah, 2011
  • BS, Chemistry, Western Washington University, 2006

Professional Affiliations

  • American Chemical Society

Job History

  • Postdoctoral Scholar University of California, Berkeley 2011-2014
  • American Heart Association Postdoctoral fellow 2013-2014
  • Assistant Professor, University of Denver 2014-present

Research

Our research group has two main areas that we are interested in and often overlap.

Small Molecule Fluorescent Probes:
Our group takes mechanistic knowledge of organic chemistry to design small pro-fluorescent molecules to detect other small molecules of biological interest. We are especially interesting in molecules that are challenging to detect with traditional organic reactions and therefore require us to use creative organometallic approaches. For example we are currently developing methods more detecting the important plant hormone ethylene. These probes have a wide variety of applications ranging from detecting increases of our analyte on the sub-cellular level to deposition on solid supports for gas phase detection.

Organic Synthesis:
Our group designs new organic reactions. In particular we are interested in organometallic transformations and controlling fundamental steps, such as migratory insertion, to provide products of interest in high yields with high selectivity. An example we are currently working on is utilizing ynol ethers in transition metal catalyzed reactions.

Key Projects

  • Fluorescent Probes for the Detection of Ethylene

Featured Publications

Awards

  • Faculty Career Champion, University of Denver